Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
A tiger for art lovers and Clive Barker fans by @hunchbacksociety
#ceramics #ceramic #ceramicart #handmade #ArtMastodon
I can't believe I missed this podcast last year: Ta-Nehisi Coates on Tony Judt
cc @mucida
🎧 👇
https://www.publicbooks.org/primary-sources-ta-nehisi-coates-on-tony-judt/
Thiago Carvalho
boosted
RT @AdrianoAguzzi
@slavov_n @cshperspectives @osvaldoics More generally, young people are well-advised to stay away from any employers who regard them simply as "helping hands", be it in academia or anywhere else. Supporting the professional development of our subordinates is our #1 task!
'Tingible body macrophages (TBMs) are tasked with apoptotic cell clearance to prevent secondary necrosis and autoimmune activation by intracellular self antigens. We show by multiple redundant and complementary methods that TBMs derive from a lymph node-resident, CD169-lineage, CSF1R-blockade-resistant precursor that is prepositioned in the follicle.'
Thiago Carvalho
boosted
¡Estamos emocionados de compartir CRISPRpedia – nuestro recurso en forma de libro de texto sobre todo lo relacionado con #CRISPR – ahora traducido al español por la estudiante graduada del IGI Angélica González-Sánchez! ¡Disfruta y comparte! http://ow.ly/rbjU50N2m26
'Here we propose best practices, quality controls and data-reporting recommendations to assist in the broad adoption of reliable quantitative workflows for single-cell proteomics. Resources and discussion forums are available at https://single-cell.net/guidelines.'
"10. Try to leave out the part that readers tend to skip. Think of what you skip reading a novel: thick paragraphs of prose you can see have too many words in them."
https://www.theguardian.com/books/2010/feb/24/elmore-leonard-rules-for-writers
Thiago Carvalho
boosted
1. WHO has issued an update on the #H5N1 situation in Cambodia. Two confirmed cases, an 11 yo girl who died & her father who remains asymptomatic. 11 other contacts tested negative. A couple of noteworthy points.
The #H5N1 virus was from a strain of H5 viruses that has been circulating in southeast Asia since 2014. This is a different strain from the one that has swept across the Americas in the past couple of years. Different strain could equal slightly different behavior.
'There are many matrilineal societies—organized through mothers rather than fathers, with name and property passed from mother to daughter—around the world. In some regions, matrilineal traditions are thought to date back thousands of years.'
Thiago Carvalho
boosted
March 5, 1512, birthday of mathematician & cartographer Gerardus Mercator 🌐
When elephants are not like E. coli:
“That time was the beginning of cloning of human genes. She (Shirley Tilghman) cloned the beta globin gene. People went to listen to her seminar (at the NIH) and she presented this amazing discovery that when looking at the electron microscope of the hybridization of the globin message and the gene that they had cloned, there was a piece of the gene that was not in the message.”
From the #EMBOPodcast with Roberto di Lauro, who was a group leader at the EMBL, a professor at the University of Naples Federico II, served as President of the Stazione Zoologica Anton Dohrn, and the scientific attaché to the Italian Embassy in London.
#EMBOPodcast
https://www.embo.org/podcasts/we-should-know-more-this-is-our-main-job/
'Here’s a new paper that tries to answer the sort of question that anyone who thinks about the evolution of living systems has asked: why do we have the biochemistry that we have? And by “we”, I mean “every single living thing on Earth”.'
https://www.science.org/content/blog-post/why-these-amino-acids-anyway
'Esse processo de radicalização está em curso em Portugal e não é simétrico: manifesta-se na direita com grande agressividade e não tem paralelo à esquerda. Por muito que se procure dizer aquelas platitudes equilibradas sobre a radicalização dos dois lados, ela não existe. Nos EUA é a mesma coisa, não é o Black Lives Matter que pode ser comparado ao ascenso do trumpismo e à sua consolidação num dos grandes partidos da democracia americana, o Partido Republicano, muito para além de Trump.'
https://www.publico.pt/2023/03/04/opiniao/opiniao/radicalizacao-assimetrica-2041086
'This irony recurs in his letters: Le Carré repeatedly offers withering indictments of the powers he served, but he never seems to cast them aside. Later in life, he wrote nostalgically to Alan Judd, a fellow novelist who once served as a soldier and diplomat, of his time at MI5 and MI6: “I miss the Office … In a sense, they are the only places, apart from writing.”
https://www.theatlantic.com/books/archive/2023/02/john-le-carre-spy-came-in-from-cold-book/673227/
"A new modification to rabies virus was recently reported to allow the mapping of connected neurons without adverse effects on the cells' health, unlike earlier versions. Here, we show that the conclusions of that study were probably incorrect and based on having used viruses that had lost the intended modification because of mutations."
#neuroscience #rabiesvirus
Thiago Carvalho
boosted
'We further demonstrated that cGAS mediated inflammation by acting as a macrophage polarization switch, which promoted peritoneal macrophages and the bone marrow–derived macrophages to the inflammatory phenotype (M1) via the mitochondrial DNA–mTORC1 pathway.'
Thiago Carvalho
boosted
From an interview with Alondra Nelson.I think this is a question that should be incorporated into graduate education:
'You probably saw the Pew study that says trust in science is still high. A significant majority of Democrats think that scientists should have a role in crafting policy. But a significant majority of Republicans think that we should just put stuff in the journals and then not be involved in how policy is implemented. I’m guessing you believe that scientists should be involved in crafting policy. How do we build more broad support for the role of scientists in policy?'
Thiago Carvalho
boosted
'In their recent paper, Sangbakembi-Ngounou et al. elegantly show that many malaria mosquitos, including Anopheles gambiae, Anopheles coluzzii, and Anopheles funestus (collectively the most important vectors in Africa), frequently bite during the daytime and in outdoor, peridomestic spaces'
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
