DaveFinlayTCD @finlayd@qoto.org

RT @ImmPRes_
flurry of updates coming your way. First up: Bach2 deletion can create super killer cytotoxic T lymphocytes. How do you ask? well it causes a massive increase in granzymes and perforin. This data from the @griffiths_lab is now up on ImmPRes #tcells #superkillers

RT @OnkTherapeutics
We’ve been named as one of BioSpaces’s NextGen 'Class of 2023', designating us as one of the most promising new life sciences companies in N.America this year. We’re driven by our purpose of pioneering optimally engineered #NKcell therapies to cure cancer.
https://www.onktherapeutics.com/onk-therapeutics-named-most-promising-company-in-biospaces-nextgen-2023-list/

RT @DrCJ_Houldcroft
My favourite study of "how often does a family with small children get a respiratory infection?" is this one, from the USA:
https://doi.org/10.1093/cid/civ486
Children <5y have one of 16 common respiratory viruses detected in a nasal swab 50% of the year!

RT @Irishimmunology
We are very excited to announce that Prof @EdLavellee is to be awarded our Annual Award for Immunology 2022 for his contributions to Irish immunology research and education!

For more information about the award you can check out our website at https://www.irishimmunology.ie/annual-award

RT @lydfinley
Do you ❤️ the TCA cycle? (trick question). Our new review discusses the origins, discovery, and many functions of the mammalian TCA cycle. By @paigearnold2 @SKI_CellBiology out now in @jbiolchem https://www.jbc.org/article/S0021-9258(22)01281-9/fulltext

RT @FearonCassidy
Our latest story from the @OSheaHoganLab is now in pre-print, I investigated the metabolic requirements for early MAIT cell responses with the help of the amazing @AndyHogan82 team @KediaMehta @RonanBergin @Andrea_W7 https://twitter.com/osheahoganlab/status/1605496087313125376

RT @cggbamford
Final output of the year, in collab w/ @mark_w_robinson @MaynoothUni and led by @gordongreville highlighting that defects in type I IFN signaling might explain why people with liver disease are more vulnerable to SARS2 infection https://www.medrxiv.org/content/10.1101/2022.12.14.22283445v1 funded by @scienceirel

RT @OSheaHoganLab
NEW PRE-PRINT! Cool new story led by @FearonCassidy on what fuels rapid #MAITcell responses like cytotoxicity. https://www.biorxiv.org/content/10.1101/2022.12.20.521164v1 Mini thread below

RT @DelgoffeLab
Thrilled to kick off the holiday season with a new paper from the lab! Out in @NatImmunol today, we explore an unexpected function of terminally exhausted T cells and their contribution to the immunosuppressive tumor microenvironment. 🧵 1/ https://www.nature.com/articles/s41590-022-01379-9

RT @AndyHogan82
New mini-review on #MAITcell metabolism - topic in its infancy but one @KediaMehta & myself think will become very important in the future https://www.frontiersin.org/articles/10.3389/fimmu.2022.1108071/abstract

RT @WimGMeijer
Very sharp increase in SARS-CoV-2 levels in Dublin wastewater. As in the previous two years, viral levels peak during the Christmas period.

Data from 24 June 2020 - 14 December 2022

@UCD_SBBS @UCD_Research @IrishWater
@HSELive @nvrlucdireland @hpscireland #wastewater

RT @stephan_till
Our paper introducing PK Mito Orange (PKMO) has finally been published. It was a great pleasure to work together with @TianyanL on this project. Wonderful collaboration between @ZhixingChen2 and @JakobsLab!

https://www.pnas.org/doi/10.1073/pnas.2215799119

#mitochondria #STED