🎓 Dr. Freemo 🇳🇱 @freemo@qoto.org

If a chemist tried to do a portrait of a person.

#Chemistry

TIL you can literally drink pure Phosphoric Acid and it wont destroy your mouth. I mean i knew it wasnt the strongest of acids but I didnt realize how weak it was.

I found this out because a vitamin I bought is 95% water and 5% pure phosphoric acid. i put a few drops out and let the water evaporate then licked it and to my surprise it was tart but didnt burn. Should have been close to 85% pure after the bulk of the water evaporated.

#Chemistry

Please #Share this to help others, thanks!

I offer free tutoring in most college level #STEM courses. Can be online, just random questions, video chat, or even in person.

If anyone needs help learning any STEM topic (even you arent in school), please reach out to me I am always happy to help. If I dont know the subject I can also maybe connect you with someone who does, but I am well versed on most of the basics like #Math, #Biology #statistics #BigData #programming #Chemistry #Medicine #ElectricalEngineering and #RF design.

Quantum Mechanics is just Assembly language for chemistry...

#chemistry #Physics #QM #QuantumMechanics

So a while back i realized you can create an extremely high energy hot plasma in the microwave consistently by taking a coil and streching it out and forming it into a loop with one gap on the sad. The ark that forms has huge amount of energy in a very small space. In the past it has melted a blob of borisilicate glass almost instantly fuzing the coil i to the glass under neath.

It has a tendency to grow into a large cloud of blasma that rises to the top of the microwave usually. Since this ball plasma is much larger the energy is spread out. Despite still being extremely hot its nowhere near the heat of the initial ark as it takes some time to heat glass to its melting point in this state.

So i had an idea. What would happen if i contained the arc under a pile of salt, in this case potassium salt. It should keep the plasma contained and due to maintaining a very small volume should retain the enormous heat i figured it would be more than hot enough to melt the salt but i wanted to try it out.

Attached is the video in the microwave itself. I will reply to this thread with various stills before and after of the setup showing the final results

#chemistry #physics #science #STEM @Science

This is what it looks like when you take cyanoacrylate and sone accelerator, through it in a pill capsule, shake them together and watch the reaction quickly harden. It gets so hard it starts smoking.

#science #chemistry #stem @Science

A friend of mine asked me why DNA and RNA are acids. I am **not** an expert in chemistry but I did study the basics of organic chem and do dabble a bit so I wanted to share the answer here.

Simple answer: Anything that lowers pH is an acid, RNA and DNA lower pH, therefore it is an acid.

Complex answer:

Nucleic Acids are called acids because, well, they lower pH, as anything that is an acid would. pH is, in simplistic terms, the concentration (logarithmicly) of H+ ions in a solution.

A unrelated side note with acids that dont directly donate a H+, your Lewis Acids, they still increase H+ in an aqueous solution because it effects the balance of H+ and OH- dissociation of the water itself. As such the H+ measure is still accurate. However Nucleic acids are not a Lewis Acid, they are a Bronstead-Lowry acid, which means they directly can dissociate and provide the H+ ion directly in an aqueous solution. But I'll get to that.

The individual parts of any molecule can be either acidic and basic, but a molecule overall will usually be one or the other depending on which dominates, RNA is no different, there are three major components to RNA, I attached a picture to show them. The components are a phosphate group, a sugar, and a nitrogenous base (the part that encodes data, your citosine and guanine and shit). Here is the cool part, the word base when talking about the "bases" of a strand is specifically chosen as the the word because they are themselves bases (on their own they would raise pH). Similarly the phosphor group, is also acidic, this should be obvious by its similarity to phosphoric acid. It is a proton donor for the same reason phosphoric acid is a proton donor.

So the only question remaining is why does the acidic phosphor group dominate over the Nitrogenous Base? Well for starters the the phosphate group has a pkA of near 0 , the Nitrogenous Base has a pkB of around 9.8 (depends on the base), so already the phosphate group is going to dissociate more readily than the Nitrogenous Group. However RNA strands are actually far more acidic than the individual Nucleotides that compose them happen to be. The reason for this is that RNA folds back in on itself with the bases associating with each other much like two halves of a DNA strand would. This causes the bases to be on the interior of the molecule while leaving the phosphate groups all around the outside. Since the bases are not exposed to the aqueous solution they do not dissociate as readily as they otherwise would while the phosphate groups are free to dissociate. Thus the RNA exhibits significant acidic properties.

By the way the acidic nature of RNA and DNA is intentional and functionally important. It means that the pH of the solution can be adjusted to effect the charge on the nucleotides and thus move it around. In a neutral pH solution the phosphate groups will have a negative charge. This results in the phosphates pushing each other away. This in turn can cause them to line up on opposite sides with their bases facing each other as well as help to straighten out a strand's backbone.

#DNA #RNA #Chemistry #Organic Chem #OChem #OrganicChemistry #Science #STEM @Science

What is your favorite multi-chemical acid formulation?

#chemistry

What is your favorite solvent?

#Chemistry

A picture of my home Organic Chemistry lab I took about 8 years ago. Its really not hard to set up a home lab, and you can buy all the fancy stuff as you go if you want, but you can do a lot with even a basic setup.

#chemistry #OrganicChemistry #Science @Science

@funny

I'm pretty sure this is an actual picture of me right before one of my ex girlfriends broke up with me.

#funny #joke #jokes #humour #humor #science @Science #chemistry

Having some fun in the lab today doing some semisynthesis on phenols using Boron Trifluoride Etherate. Everything should be done except the final distillation step ill be doing tomorrow.

#chemistry #organicchemistry #ochem #science

Some of the better #science related bad stock photos

#BadStockPhotos #astronomy #chemistry

Ok so after a day of running TLC plates on this experiment and continually failing to separate out the THC and th CBD on the plate I decided to give up and wait for a more appropriate stain that colors differently for THC and CBD to help that along...

In the meantime just to be sure I did do a colorimetric test called the beam test which can distinguish between CBD and THC nad I can show the final product has relatively no CBD in it.

The picture below shows the before and after sample tested side by side. The vial on the right was the vial that held the pure CBD (just had a little residual dust in it). It turned pink and then a dark violet. The watch glass on the left as the final isomerized product. It remains clear indication no CBD is present in the sample, this strongly suggests it is a relatively pure sample of THC.

#Science #chemistry #OChemistry #Cannabis

The TLC plate i was trying didnt quite work. I think it wasnt ling enough to allow the chemicals to seperate. This one is a bit ugly as i had to cut it but its 3 tines longer. Maybe this will work...

#Chemistry #OrganicChemistry #Ochem #Science

Who said scientists cant be poets?

#Science #Chemistry

Today I finished the first 1/3rd of the video I am doing for all of you showing CBD to THC semisynthesis. I should be able to finish the rest tomorrow I hope.

Today I covered dissolving the CBD in hexane in the proper proportion then stepped everyone through the steps to do a TLC plate on it so we can verify the purity of the starting product, which includes how to stain it to help CBD develop a distinct pink color for easier identification.

Tomorrow I will do the semi-synthesis into THC and then the final analysis to prove the end result.

I attached a sneak peek at what the TLC play to identify pure CBD looks like after it is developed. That pink dot indicates pure CBD.

#chemistry #Ochem #OrganicChemistry #science

I just made up some vanillin stain for the CBD -> THC synthesis I promised everyone, recorded it and all.

Man I do love the smell though! Vanillin is the best stuff ever!

#Chemistry #OChem #OrganicChemistry

My mom spent the whole day with me while I cleaned the Organic Chemistry lab. Also some important chemicals came in.

I know I keep promising this but I'm getting very close to being able to demonstrate to everyone the semisynthesis of CBD to THC!

#Science #Chemistry #OChem #OrganicChemistry

The hexane just arrived for the CBD to THC synthesis lan ill be showing sometime later this week!

#Science #Chemistry #OrganicChemistry