Multiple studies have proven the impact of #endocrine #disruptors, e.g. #phthalates and #parabens, on #thyroid #homeostasis. It was unknown, however, that these effects depend on whether or not the included persons are fasting.
Weltweit und gleichzeitig radikalisieren sich Teile der Bevölkerung und driften nach rechts. Was ist die Ursache?
Neben maschineller Probaganda könnte auch der negative #Flynn-Effekt eine Rolle spielen, eine Intelligenzabnahme durch endokrine #Disruptoren.
https://blog.endokrinologie.net/intelligenzabnahme-flynn-effekt-4157/
Growing evidence supports a role of sensorimotor and autonomic #neuropathy in #syndrome_T or #SORSHOT, i.e. reduced quality of life in treated #hypothyroidism. #SPINA_GT and #SPINA_GD predict nerve function and depression.
The hazardous impact of #parabens on #thyroid #homeostasis (HPT axis) affects several elements of the feedback loop.
Again, a study showed a strong influence of endocrine disruptors on #thyroid homeostasis. Exposure to butylparaben significantly reduces #SPINA-GD, whereas ethylparaben slightly increases #SPINA_GT in pregnancy.
About 10% of hypothyroid patients have reduced quality of life despite normal TSH concentration under therapy with levothyroxine (L-T4). A new randomised, double-blind trial demonstrated better QoL under L-T4 + L-T3 compared to L-T4 alone.
Teilnehmer:innen gesucht! Klinische Studie zur Verbesserung der #Insulintherapie bei #Diabetes mellitus Typ 1.
https://www.klinikum-bochum.de/fachbereiche/innere-medizin/diabetologie/insulin-studie.html
Digitale Zwillinge in der Endokrinologie: Der Weg zu einer prädiktiven und personalisierten Medizin. 🧪🩺
https://blog.endokrinologie.net/digitale-zwillinge-in-der-endokrinologie-5717/
Hintergrundartikel zum Thema in diabetologie-online:
#Smartwatches mit nichtinvasiver #Glukosemessung, ohne Stich, zuverlässig und günstig? Zu schön, um wahr zu sein! Untersuchungen des Instituts für #Diabetestechnologie in Ulm legen den Betrug offen. Selbst auf einer Banane wird ein #Blutzucker "gemessen". 🩺🧪
https://www.ifdt-ulm.de/fileadmin/website/Video_Content/Smartwatches_deutsch2.mp4
Endocrine disruptors have a strong effect on the peripheral #thyroid hormone metabolism. A recent study showed a nonlinear dose-response relationship between #PFAS and step-up deiodinase activity (#SPINA_GD).
https://pubmed.ncbi.nlm.nih.gov/39556482/
https://doi.org/10.1210/clinem/dgae798
Assessing diagnostic tools in #endocrinology with computer simulations https://link.medium.com/qDCugbiYZMb
Einladung zur 2. Endokrinologischen Abendsprechstunde "Up-to-date Schilddrüse 2024" am 25. September 2024.
#Schilddrüse #Nebenschilddrüse #Hypothyreose #Schilddrüsenchirurgie #Syndrom_T #SORSHOT
http://www.endokrinologie.org/resources/flyer-up-to-date-schilddruse-2024.pdf
#Metformin is a useful antidiabetic substance, but also an endocrine disruptor. A recent study shows that it reduces the set point of #thyroid homeostasis, but this effect is mitigated by #vitamin_D deficiency.
https://pubmed.ncbi.nlm.nih.gov/39204438/
https://doi.org/10.3390/pharmaceutics16081093
@josemanuel
No, but Lisp is one of my favourite languages. I should give it a try.
Which programming language is fit for high-performance computer simulations in biomedical #cybernetics? We found that #Free_Pascal generates faster code than S/R and #Python. Interestingly, Object #Pascal even outperforms #Swift and C++.
https://doi.org/10.14201/adcaij.31762
https://revistas.usal.es/cinco/index.php/2255-2863/article/view/31762
Both sensorimotor and autonomic #neuropathy may be common in #hypothyroidism, despite treatment.
#Inflammation plays a key role in the pathogenesis of #diabetes mellitus. In our newest paper, we show that treatment of #hidradenitis_suppurativa (#acne_inversa) may cause remission of diabetes. CN: medical images in full text. https://pubmed.ncbi.nlm.nih.gov/39106221/ https://doi.org/10.1111/ddg.15490
Die Grafen von #Neuburg-#Falkenstein waren ein bedeutendes Adelsgeschlecht der #Stauferzeit. Ihr Gebiet reichte von Oberbayern bis Südtirol und Niederösterreich. Ihre Stammburg #Unterfalkenstein wurde bei dem bayerischen #Hochwasser schwer beschädigt. #Klima
apl. Prof. Dr. med. Johannes Dietrich, endocrinologist, head of the diabetes, endocrinology and metabolism section of #KKB @RUBMedizin. Views are my own.