behind "hello world" on Linux https://jvns.ca/blog/2023/08/03/behind--hello-world/
'She had consented to be a part of our research project and was determined to contribute — she had told me that it wasn’t every day that a person had electrodes implanted in their brain, and what else was she doing while she waited to have seizures that the epileptologists could track?'
What if we told you that you could run Fedora... on Android? 👀
#Fedora #Android #Linux #Termux
➡️ https://fedoramagazine.org/how-to-install-and-update-fedora-linux-on-android-using-termux/
First post of my summer blog series on image communication in (bio/med) publications!
Today: Many papers, many images, many problems (and some first solutions).
Why we should make sure our figure are understandable.
The more I work with #rstats, the less I know about it!
Today I learned about the function utils::stack() to convert a named list to a data frame.
R-Ladies Remote is now on Mastodon 🎉
We are the only fully online chapter of R-Ladies, the global organization promoting gender diversity in the R community. Our chapter particularly welcomes people working remotely or living in places remote from other chapters.
Our main community is on Slack, where we sometimes hold organized sessions (coffee chats, reading groups) and we also hold occasional online talks/workshops.
The most disappointingly simplistic thinking in tech, to me personally, is when people think just because something is being deployed IN education, in a classroom, or in a school, that means it's an unquestionable public good.
Instead of seeing the many, many complex ways that we take advantage of schools, or indeed damage schools, with our technology.
I'm always amazed by the strength of this association for people who haven't worked directly in education.
Underlying problem is that we literally have college courses in noise mining (we call them Stats 101) so millions of scientists are out there noise mining, and so we have a lot of papers that really do have low evidentiary value. It's not because they're not preregistered, it's because the people doing the analysis wouldn't know what a good analysis looked like, and in fact would likely fight a good analysis tooth and nail.
I wrote a script that takes as input a gene of interest:
```console
./script/plot_heatmap.sh -p 10 TP53
```
and generates a gene expression heatmap with genes that have correlated expression patterns.
Behind the scenes is a Bash script (calling `gget`) and a #Rstats script available at https://github.com/davetang/archs4_heatmap
Scientists whose first language is not English spend much longer to read and write papers in English and prepare for international conferences. @tatsuya_amano and colleagues worked to measure this invisible struggle. I wrote about their work for @nature https://www.nature.com/articles/d41586-023-02320-2
One of my professors during PhD used to say “you can drive a truck through the holes in any given paper. so you look for what you *can* learn instead.” and being the smartass grad students we used to think driving that truck was fun. After so many years, I now appreciate her wisdom more than ever. All scholarly work has limitations but it’s refreshing when people critically evaluate what’s the actual value of the research. It's about humility, honesty, rigorous intellectual work.
Very happy to share our newly published #article "Sex differences in pituitary corticotroph excitability".
It is well known that sex differences exist in stress-related disorders, with women having twice the lifetime rate of depression compared to men and most anxiety disorders.
Corticotroph cells in the pituitary gland are a key player in the generation of hormonal stress responses. However, their contribution to sexually differential responses of the stress axis (which might underlie differences in stress-related disorders) is very poorly understood.
We found sex differences in the electrical activity of these cells, which could be related to differences in their gene expression pattern.
These findings shed light on the cellular mechanisms underlying sex differences in stress responses, contributing to a better understanding of stress-related disorders and potential avenues for diagnosis and treatment.
#stress #pituitary #research #electrophysiology #physiology #corticotrophs #hpa #anxiety
https://www.frontiersin.org/articles/10.3389/fphys.2023.1205162/full
New posting! This addresses the recent controversy at the 2023 Lindau Nobel Laureate meeting, where one of the speakers used his time to complain that he felt discriminated against as a white man.
To my mind, that isn't what's surprising and shocking about the episode.
The surprising thing is that on this occasion, a courageous young female scientist actually called him out on it.
The shocking thing is that despite such sexist, chauvinistic comments still being commonplace, such interventions basically never happen. And they should. #womeninstem
Many prominent anti-vaccine influencers claim biomedical credentials. In a new pre-print, we quantify the size & influence of the group of perceived experts in the anti-vaccine community on Twitter.
https://www.medrxiv.org/content/10.1101/2023.07.12.23292568v1.full.pdf+html
Bad values dont me new values... A good person encouraging education to children is just as good a person regardless if they wear pants or a dress... THAT is a good value to teach kids.
@admitsWrongIfProven @iDoobyLeaves@noagendasocial.com
Microsoft "confirmed Tuesday that its validation procedure had been manipulated to digitally sign dozens of pieces of software."
Microsoft, Adobe, these firms have autoupdaters, installed on so many of our machines, that will run without question code signed by the mothership.
That's bad enough. How much should you trust Microsoft, both its intentions and internal security?
It's absolutely terrifying that hostile third parties have managed it. https://www.washingtonpost.com/national-security/2023/07/12/microsoft-hack-china/
ht @GossiTheDog
reanalyzerGSE: tackling the everlasting lack of reproducibility and reanalyses in transcriptomics https://www.biorxiv.org/content/10.1101/2023.07.12.548663v1?med=mas
Really not enjoying this “will they won’t they”. UK science is at stake. Sunak and von der Leyen fail to agree Horizon Europe deal.
https://www.researchprofessionalnews.com/rr-news-uk-politics-2023-7-sunak-and-von-der-leyen-fail-to-agree-horizon-europe-deal/
Senior lecturer at the Zhejiang-Edinburgh Joint Institute (ZJE) and Edinburgh University.
Undergraduate Programme Director, Biomedical Informatics at ZJE.
I teach #imageanalysis & #dataanalysis with #RStats & #python. I study #heterogeneity in #pituitary (and other) cells.
I'm also very interested in #reproducibility and #openscience.