An excellent overview on #coxsackievirus targeting drugs.
https://onlinelibrary.wiley.com/doi/epdf/10.1002/rmv.2406
Hello Mastodon! This is the official account for the European Society of Clinical Microbiology and Infectious Diseases (ESCMID).
We are a non-profit org focused on #InfectiousDisease and Clinical Microbiology for professionals in those areas.
We organise research grants, educational events and our annual congress #ECCMID2023 (www.eccmid.org) along with much more.
You can learn all about us on our website (www.escmid.org) and we hope to see you around!
Another excellent business opportunity for our birdy-friend: https://pubs.acs.org/doi/10.1021/cen-10040-cover
RT @UZH_Chemistry@twitter.com
@Simon__Sieber@twitter.com and co-authors @UZH_Chemistry@twitter.com developed the first catch-enrich-release approach that results underivatized amine-containing compounds as products published @ChemCommun@twitter.com: https://pubs.rsc.org/en/content/articlelanding/2022/CC/D2CC04905H
🐦🔗: https://twitter.com/UZH_Chemistry/status/1592509956217266178
Animal models for long Covid, review at #PlosPathogens
"We review SARS-CoV-2 infection and disease manifestations in mice, Syrian hamsters, ferrets, and nonhuman primates (NHPs). Specifically, the virology, pathology, immune responses, and multiorgan involvement are summarized. These models are rationally examined for their use in understanding the complexities of the multiorgan involvement during Long COVID and the potential for their use in screening therapeutics such as anti-inflammatory drugs, which are currently used for treating other diseases. The aim of this review is to highlight Long COVID preclinical animal models that could be used for Long COVID research and to screen for pharmacological interventions."
#Covid19 #LongCovid #Covid #SarsCoV2
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1010741
I'm an assistant #Professor at the University of York. I lead a team researching how steroid hormones drive breast cancer tumour growth.
I've shifted fields a lot over my career, originally I was an organic chemist, and then during my #PhD I used those skills to look at bacteria that make antibiotics.
With the growth of 'omics technologies, I got into #genomics and #proteomics which now underpins our cancer research work.
See link for nice curated lists of academics on Mastodon, with subjects ranging from Astrophysics to History to Law to Medieval History to Neuroscience.
Thank you to @hendrikerz and @perspektivbrocken for maintaining it.
We are looking for one or two more post-docs to work on the role of inner membrane association in Vibrio cholerae transcription regulation or communication between the host intestine and intestinal bacteria. Your pic here?😁 https://paulawatnicklab.com for contact info
Intro: Currently lead of Research IT at a large BioTech located in Boston Seaport. Prior: Led automation, data sci, catalysis, HTE crystallization, and biocatalysis group in process chemistry at BMS for 10 years. Before was at Merck process working in biocatalysis (claim to fame was leading the transaminase development for sitagliptin manufacture). Ph.D. Organic Chemsitry (Harvard, Dave Evans 2003). B.S. Chemistry (UChicago, Rawal 1998) #ChemiVerse
Possible applications of #MultiTarget compounds in #ProxPharm Beyond PROTACs.
https://www.sciencedirect.com/science/article/pii/S2001037022005049
What is Mastodon?
What are the pros and cons of Mastodon over Twitter?
Should I make the switch?
All that and more in our latest blog!
#academia #PhD #science #xp @OpenAcademics @AcademicChatter
Read it here:
https://thestrugglingscientists.com/mastodon-for-academics/
#Introduction — I am a Professor of #EvolutionaryBiology at #UniversityOfManchester UK. My lab studies the #evolution and #ecology of microbes and microbial communities. We mostly use #ExperimentalEvolution and #Genomics
#adaptation #diversification #coevolution #symbiosis #mutualism #parasitism #microbiome #MicrobialGenomics #HorizontalGeneTransfer #HGT #plasmid #phage #bacteria #protists #algae #Pseudomonas #AntimicrobialResistance #AMR #CysticFibrosis #bronchiectasis
Hi there! My name is Cedric and I'm a synthetic medicinal chemist. I design and develop new molecules hoping to find something useful to treat neglected tropical diseases such as #Malaria, #Leishmaniasis and #Chagas disease.
Currently I am a #MedicinalChemistry trainer at the Wellcome Centre for Anti-Infectives Research at the University of Dundee, Scotland. My interests are #chemistry, #DrugDesign, #compchem and some #python on the side.
-Time for a short #Introduction-
I am a group leader in #MedicinalChemistry at the University of Parma. My lab combines #chemical & #computational techniques to develop novel pharmacological tools to study different Chronic Diseases (#CysticFibrosis, #IBD, #Hypercholesterolemia, #Alzheimer, #Cancer) and Infective Agents (#SARSCoV2, #Enterovirus, #Flavivirus, #Monkeypox, #HIV).
We are particularly interested in the development of #MultiTarget inhibitors and open to new #collaborations in #DrugDiscovery.
#Tooting (sooner or later) about the #chemistry and #science
Hi #ChemiVerse
I might come to regret this, but I've seen some journalists compiling lists of people on here & I thought it might be useful in the early days here to do something similar for the chemistry community (& those who interact with the chemistry community – you can define that quite liberally).
So, here is a Google Form that you can fill in if you wish: https://forms.gle/gF9MLUGMWs23EFix6
And it feeds into this Google Sheet: https://docs.google.com/spreadsheets/d/1qdJvHHvu-BC4N6nk1jNMhTwoBrIaqHLUCZRf9pCQwDs/edit?usp=sharing
(The form does not collect e-mail addresses)
The researchers Twitter migration to #Mastodon is taking shape and has its own paper in Science!
"As Musk reshapes Twitter, academics ponder taking flight.
Many researchers are setting up profiles on social media site Mastodon".
https://www.science.org/content/article/musk-reshapes-twitter-academics-ponder-taking-flight
Professor of Medicinal Chemistry at the University of Parma (Italy).
Developing novel drug candidates for Chronic and Infective Diseases.
Interests:
#MedChem #MedicinalChemistry #DrugDiscovery #Chemistry #MultiTarget #Antiviral #Antibacterial #Anticancer #IBD #CVD #Alzheimer #CysticFibrosis #Medicine #Pharmacology #Biotech #ccr6 #pcsk9 #bsaa